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The Cellular Localization of Human Cytomegalovirus Glycoprotein Expression Greatly Influences the Frequency and Functional Phenotype of Specific CD4(+) T Cell Responses
CMV infection is a significant cause of morbidity and mortality in immunocompromised individuals, and the development of a vaccine is of high priority. Glycoprotein B (gB) is a leading vaccine candidate but the glycoprotein H (gH) pentameric complex is now recognized as the major target for neutrali...
Autores principales: | Pachnio, Annette, Zuo, Jianmin, Ryan, Gordon B., Begum, Jusnara, Moss, Paul A. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592104/ https://www.ncbi.nlm.nih.gov/pubmed/26363059 http://dx.doi.org/10.4049/jimmunol.1500696 |
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