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Amyloid-Related Memory Decline in Preclinical Alzheimer’s Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months
High levels of β-amyloid (Aβ) in the brain and carriage of the APOE ε4 allele have each been linked to cognitive impairment in cognitively normal (CN) older adults. However, the relationship between these two biomarkers and cognitive decline is unclear. The aim of this study was to investigate the r...
Autores principales: | Thai, Christine, Lim, Yen Ying, Villemagne, Victor L., Laws, Simon M., Ames, David, Ellis, Kathryn A., Rainey-Smith, Stephanie R., Martins, Ralph N., Masters, Colin L., Rowe, Christopher C., Maruff, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592244/ https://www.ncbi.nlm.nih.gov/pubmed/26430784 http://dx.doi.org/10.1371/journal.pone.0139082 |
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