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Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding Proteins

Elevated plasma low-density lipoprotein (LDL) cholesterol is considered as a risk factor for atherosclerosis. Because the hepatic LDL receptor (LDLR) uptakes plasma lipoproteins and lowers plasma LDL cholesterol, the activation of LDLR is a promising drug target for atherosclerosis. In the present s...

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Detalles Bibliográficos
Autores principales:	Ochiai, Ayasa, Miyata, Shingo, Shimizu, Makoto, Inoue, Jun, Sato, Ryuichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592265/ https://www.ncbi.nlm.nih.gov/pubmed/26431033 http://dx.doi.org/10.1371/journal.pone.0139799

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