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Methotrexate administration directly into the fourth ventricle in children with malignant fourth ventricular brain tumors: a pilot clinical trial

We hypothesize that chemotherapy can be safely administered directly into the fourth ventricle to treat recurrent malignant brain tumors in children. For the first time in humans, methotrexate was infused into the fourth ventricle in children with recurrent, malignant brain tumors. A catheter was su...

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Detalles Bibliográficos
Autores principales: Sandberg, David I., Rytting, Michael, Zaky, Wafik, Kerr, Marcia, Ketonen, Leena, Kundu, Uma, Moore, Bartlett D., Yang, Grace, Hou, Ping, Sitton, Clark, Cooper, Laurence J., Gopalakrishnan, Vidya, Lee, Dean A., Thall, Peter F., Khatua, Soumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592494/
https://www.ncbi.nlm.nih.gov/pubmed/26255071
http://dx.doi.org/10.1007/s11060-015-1878-y