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Enzyme Polymorphism in Warfarin Dose Management After Pediatric Cardiac Surgery

BACKGROUND: Warfarin is an anticoagulant and is widely used for the prevention of thromboembolic events. Genetic variants of the enzymes that metabolize warfarin, i.e. cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1), contribute to differences in patients’ responses to various w...

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Detalles Bibliográficos
Autores principales: Tabib, Avisa, Najibi, Babak, Dalili, Mohammad, Baghaei, Ramin, Poopak, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592525/
https://www.ncbi.nlm.nih.gov/pubmed/26448196
http://dx.doi.org/10.5812/cardiovascmed.27963v2