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Application of a Systems Pharmacology-Based Placebo Population Model to Analyze Long-Term Data of Postmenopausal Osteoporosis

Osteoporosis is a progressive bone disease characterized by decreased bone mass resulting in increased fracture risk. The objective of this investigation was to test whether a recently developed disease systems analysis model for osteoporosis could describe disease progression in a placebo-treated p...

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Detalles Bibliográficos
Autores principales: Berkhout, J, Stone, JA, Verhamme, KM, Stricker, BH, Sturkenboom, MC, Danhof, M, Post, TM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592531/
https://www.ncbi.nlm.nih.gov/pubmed/26451331
http://dx.doi.org/10.1002/psp4.12006