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Defining the fitness of HIV-1 isolates with dual/mixed co-receptor usage

BACKGROUND: CCR5-using (r5) HIV-1 predominates during asymptomatic disease followed by occasional emergence of CXCR4-using (x4) or dual tropic (r5x4) virus. We examined the contribution of the x4 and r5 components to replicative fitness of HIV-1 isolates. METHODS: Dual tropic r5x4 viruses were predi...

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Detalles Bibliográficos
Autores principales:	Nankya, Immaculate L, Tebit, Denis M, Abraha, Awet, Kyeyune, Fred, Gibson, Richard, Jegede, Oyebisi, Nickel, Gabrielle, Arts, Eric J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592561/ https://www.ncbi.nlm.nih.gov/pubmed/26435727 http://dx.doi.org/10.1186/s12981-015-0066-7

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