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The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran

Background. Metabolic control is an important factor in growth of children with type I diabetes. This study assessed the relationship between growth and metabolic control in such children. Materials and Methods. 83 children with diabetes were studied. They were examined for weight and height gain an...

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Autores principales: Assar, Shide, Riahi, Koroush, Bashirnezhad, Shiva, Yazdanpanah, Leila, Latifi, Seyed Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592738/
https://www.ncbi.nlm.nih.gov/pubmed/26457227
http://dx.doi.org/10.1155/2015/917542
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author Assar, Shide
Riahi, Koroush
Bashirnezhad, Shiva
Yazdanpanah, Leila
Latifi, Seyed Mahmoud
author_facet Assar, Shide
Riahi, Koroush
Bashirnezhad, Shiva
Yazdanpanah, Leila
Latifi, Seyed Mahmoud
author_sort Assar, Shide
collection PubMed
description Background. Metabolic control is an important factor in growth of children with type I diabetes. This study assessed the relationship between growth and metabolic control in such children. Materials and Methods. 83 children with diabetes were studied. They were examined for weight and height gain and HbA1C was quantified every 3 months for one year. The growth process was studied in patients who were divided into 3 groups according to their HbA1C amounts, consisting of good, intermediate, and poor metabolic control. Results. Mean age of cases was 7.6 ± 2. The presenting sign at the onset of disease was diabetic ketoacidosis in 44.6%. The average HbA1C amount was 8.89%. The average weight SDS at diagnosis was −0.18 and at the end of the study was 0.45 (P<0.001). The average height SDS at diagnosis was −0.04 and at the end of the study was −0.07 (P=0.64). A significant difference in weight SDS changes was only seen between patients with good and poor metabolic control (P=0.04). Conclusion. Poor metabolic control can decrease height growth but has minimal influence on weight. Metabolic control was not the only predictive factor of physical growth in children with diabetes.
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spelling pubmed-45927382015-10-11 The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran Assar, Shide Riahi, Koroush Bashirnezhad, Shiva Yazdanpanah, Leila Latifi, Seyed Mahmoud Scientifica (Cairo) Research Article Background. Metabolic control is an important factor in growth of children with type I diabetes. This study assessed the relationship between growth and metabolic control in such children. Materials and Methods. 83 children with diabetes were studied. They were examined for weight and height gain and HbA1C was quantified every 3 months for one year. The growth process was studied in patients who were divided into 3 groups according to their HbA1C amounts, consisting of good, intermediate, and poor metabolic control. Results. Mean age of cases was 7.6 ± 2. The presenting sign at the onset of disease was diabetic ketoacidosis in 44.6%. The average HbA1C amount was 8.89%. The average weight SDS at diagnosis was −0.18 and at the end of the study was 0.45 (P<0.001). The average height SDS at diagnosis was −0.04 and at the end of the study was −0.07 (P=0.64). A significant difference in weight SDS changes was only seen between patients with good and poor metabolic control (P=0.04). Conclusion. Poor metabolic control can decrease height growth but has minimal influence on weight. Metabolic control was not the only predictive factor of physical growth in children with diabetes. Hindawi Publishing Corporation 2015 2015-09-20 /pmc/articles/PMC4592738/ /pubmed/26457227 http://dx.doi.org/10.1155/2015/917542 Text en Copyright © 2015 Shide Assar et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Assar, Shide
Riahi, Koroush
Bashirnezhad, Shiva
Yazdanpanah, Leila
Latifi, Seyed Mahmoud
The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title_full The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title_fullStr The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title_full_unstemmed The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title_short The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran
title_sort relationship between metabolic control and growth in children with type i diabetes mellitus in southwest of iran
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592738/
https://www.ncbi.nlm.nih.gov/pubmed/26457227
http://dx.doi.org/10.1155/2015/917542
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