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Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength

Titanium and its alloys have become the most attractive implant materials due to their high corrosion resistance, excellent biocompatibility and relatively low elastic modulus. However, the current Ti materials used for implant applications exhibit much higher Young’s modulus (50 ~ 120 GPa) than hum...

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Autores principales: Guo, Shun, Meng, Qingkun, Zhao, Xinqing, Wei, Qiuming, Xu, Huibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592961/
https://www.ncbi.nlm.nih.gov/pubmed/26434766
http://dx.doi.org/10.1038/srep14688
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author Guo, Shun
Meng, Qingkun
Zhao, Xinqing
Wei, Qiuming
Xu, Huibin
author_facet Guo, Shun
Meng, Qingkun
Zhao, Xinqing
Wei, Qiuming
Xu, Huibin
author_sort Guo, Shun
collection PubMed
description Titanium and its alloys have become the most attractive implant materials due to their high corrosion resistance, excellent biocompatibility and relatively low elastic modulus. However, the current Ti materials used for implant applications exhibit much higher Young’s modulus (50 ~ 120 GPa) than human bone (~30 GPa). This large mismatch in the elastic modulus between implant and human bone can lead to so-called “stress shielding effect” and eventual implant failure. Therefore, the development of β-type Ti alloys with modulus comparable to that of human bone has become an ever more pressing subject in the area of advanced biomedical materials. In this study, an attempt was made to produce a bone-compatible metastable β-type Ti alloy. By alloying and thermo-mechanical treatment, a metastable β-type Ti-33Nb-4Sn (wt. %) alloy with ultralow Young’s modulus (36 GPa, versus ~30 GPa for human bone) and high ultimate strength (853 MPa) was fabricated. We believe that this method can be applied to developing advanced metastable β-type titanium alloys for implant applications. Also, this approach can shed light on design and development of novel β-type titanium alloys with large elastic limit due to their high strength and low elastic modulus.
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spelling pubmed-45929612015-10-19 Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength Guo, Shun Meng, Qingkun Zhao, Xinqing Wei, Qiuming Xu, Huibin Sci Rep Article Titanium and its alloys have become the most attractive implant materials due to their high corrosion resistance, excellent biocompatibility and relatively low elastic modulus. However, the current Ti materials used for implant applications exhibit much higher Young’s modulus (50 ~ 120 GPa) than human bone (~30 GPa). This large mismatch in the elastic modulus between implant and human bone can lead to so-called “stress shielding effect” and eventual implant failure. Therefore, the development of β-type Ti alloys with modulus comparable to that of human bone has become an ever more pressing subject in the area of advanced biomedical materials. In this study, an attempt was made to produce a bone-compatible metastable β-type Ti alloy. By alloying and thermo-mechanical treatment, a metastable β-type Ti-33Nb-4Sn (wt. %) alloy with ultralow Young’s modulus (36 GPa, versus ~30 GPa for human bone) and high ultimate strength (853 MPa) was fabricated. We believe that this method can be applied to developing advanced metastable β-type titanium alloys for implant applications. Also, this approach can shed light on design and development of novel β-type titanium alloys with large elastic limit due to their high strength and low elastic modulus. Nature Publishing Group 2015-10-05 /pmc/articles/PMC4592961/ /pubmed/26434766 http://dx.doi.org/10.1038/srep14688 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Guo, Shun
Meng, Qingkun
Zhao, Xinqing
Wei, Qiuming
Xu, Huibin
Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title_full Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title_fullStr Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title_full_unstemmed Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title_short Design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
title_sort design and fabrication of a metastable β-type titanium alloy with ultralow elastic modulus and high strength
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592961/
https://www.ncbi.nlm.nih.gov/pubmed/26434766
http://dx.doi.org/10.1038/srep14688
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