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Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression
Most genomic-enabled prediction models developed so far assume that the response variable is continuous and normally distributed. The exception is the probit model, developed for ordered categorical phenotypes. In statistical applications, because of the easy implementation of the Bayesian probit or...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592994/ https://www.ncbi.nlm.nih.gov/pubmed/26290569 http://dx.doi.org/10.1534/g3.115.021154 |
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author | Montesinos-López, Osval A. Montesinos-López, Abelardo Crossa, José Burgueño, Juan Eskridge, Kent |
author_facet | Montesinos-López, Osval A. Montesinos-López, Abelardo Crossa, José Burgueño, Juan Eskridge, Kent |
author_sort | Montesinos-López, Osval A. |
collection | PubMed |
description | Most genomic-enabled prediction models developed so far assume that the response variable is continuous and normally distributed. The exception is the probit model, developed for ordered categorical phenotypes. In statistical applications, because of the easy implementation of the Bayesian probit ordinal regression (BPOR) model, Bayesian logistic ordinal regression (BLOR) is implemented rarely in the context of genomic-enabled prediction [sample size (n) is much smaller than the number of parameters (p)]. For this reason, in this paper we propose a BLOR model using the Pólya-Gamma data augmentation approach that produces a Gibbs sampler with similar full conditional distributions of the BPOR model and with the advantage that the BPOR model is a particular case of the BLOR model. We evaluated the proposed model by using simulation and two real data sets. Results indicate that our BLOR model is a good alternative for analyzing ordinal data in the context of genomic-enabled prediction with the probit or logit link. |
format | Online Article Text |
id | pubmed-4592994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Genetics Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-45929942015-10-15 Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression Montesinos-López, Osval A. Montesinos-López, Abelardo Crossa, José Burgueño, Juan Eskridge, Kent G3 (Bethesda) Genomic Selection Most genomic-enabled prediction models developed so far assume that the response variable is continuous and normally distributed. The exception is the probit model, developed for ordered categorical phenotypes. In statistical applications, because of the easy implementation of the Bayesian probit ordinal regression (BPOR) model, Bayesian logistic ordinal regression (BLOR) is implemented rarely in the context of genomic-enabled prediction [sample size (n) is much smaller than the number of parameters (p)]. For this reason, in this paper we propose a BLOR model using the Pólya-Gamma data augmentation approach that produces a Gibbs sampler with similar full conditional distributions of the BPOR model and with the advantage that the BPOR model is a particular case of the BLOR model. We evaluated the proposed model by using simulation and two real data sets. Results indicate that our BLOR model is a good alternative for analyzing ordinal data in the context of genomic-enabled prediction with the probit or logit link. Genetics Society of America 2015-08-18 /pmc/articles/PMC4592994/ /pubmed/26290569 http://dx.doi.org/10.1534/g3.115.021154 Text en Copyright © 2015 Montesinos-López et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Genomic Selection Montesinos-López, Osval A. Montesinos-López, Abelardo Crossa, José Burgueño, Juan Eskridge, Kent Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title | Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title_full | Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title_fullStr | Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title_full_unstemmed | Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title_short | Genomic-Enabled Prediction of Ordinal Data with Bayesian Logistic Ordinal Regression |
title_sort | genomic-enabled prediction of ordinal data with bayesian logistic ordinal regression |
topic | Genomic Selection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592994/ https://www.ncbi.nlm.nih.gov/pubmed/26290569 http://dx.doi.org/10.1534/g3.115.021154 |
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