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Identification and Correction of Sample Mix-Ups in Expression Genetic Data: A Case Study
In a mouse intercross with more than 500 animals and genome-wide gene expression data on six tissues, we identified a high proportion (18%) of sample mix-ups in the genotype data. Local expression quantitative trait loci (eQTL; genetic loci influencing gene expression) with extremely large effect we...
Autores principales: | Broman, Karl W., Keller, Mark P., Broman, Aimee Teo, Kendziorski, Christina, Yandell, Brian S., Sen, Śaunak, Attie, Alan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592999/ https://www.ncbi.nlm.nih.gov/pubmed/26290572 http://dx.doi.org/10.1534/g3.115.019778 |
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