SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers

BACKGROUND: The functional single nucleotide polymorphism (SNP) in the MDM2 promoter region, SNP309, is known to be associated with various diseases, particularly cancer. Although many studies have been performed to demonstrate the mechanism of allele-specific expression (ASE) on SNP309, they have o...

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Detalles Bibliográficos
Autores principales: Okamoto, Kanako, Tsunematsu, Ryosuke, Tahira, Tomoko, Sonoda, Kenzo, Asanoma, Kazuo, Yagi, Hiroshi, Yoneda, Tomoko, Hayashi, Kenshi, Wake, Norio, Kato, Kiyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593204/
https://www.ncbi.nlm.nih.gov/pubmed/26293665
http://dx.doi.org/10.1186/s12881-015-0216-8

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