Cargando…

Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

BACKGROUND: In family-based association analysis, each family is typically ascertained from a single proband, which renders the effects of ascertainment bias heterogeneous among family members. This is contrary to case–control studies, and may introduce sample or ascertainment bias. Statistical effi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Suyeon, Lee, Sungyoung, Lee, Young, Herold, Christine, Hooli, Basavaraj, Mullin, Kristina, Park, Taesung, Park, Changsoon, Bertram, Lars, Lange, Christoph, Tanzi, Rudolph, Won, Sungho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593209/ https://www.ncbi.nlm.nih.gov/pubmed/26286599 http://dx.doi.org/10.1186/s12881-015-0198-6

Ejemplares similares

Family-based Association Analyses of Imputed Genotypes Reveal Genome-Wide Significant Association of Alzheimer’s disease with OSBPL6, PTPRG and PDCL3
por: Herold, Christine, et al.
Publicado: (2016)

A current view of Alzheimer's disease
por: Hooli, Basavaraj V, et al.
Publicado: (2009)

Comparing family-based rare variant association tests for dichotomous phenotypes
por: Wang, Longfei, et al.
Publicado: (2016)

Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants
por: Won, Sungho, et al.
Publicado: (2015)

Integration of a Large-Scale Genetic Analysis Workbench Increases the Accessibility of a High-Performance Pathway-Based Analysis Method
por: Lee, Sungyoung, et al.
Publicado: (2018)

BALLI: Bartlett-adjusted likelihood-based linear model approach for identifying differentially expressed genes with RNA-seq data
por: Park, Kyungtaek, et al.
Publicado: (2019)

HisCoM-GGI: Software for Hierarchical Structural Component Analysis of Gene-Gene Interactions
por: Choi, Sungkyoung, et al.
Publicado: (2018)

HisCoM-PCA: software for hierarchical structural component analysis for pathway analysis based using principal component analysis
por: Jiang, Nan, et al.
Publicado: (2020)

Hierarchical structural component model for pathway analysis of common variants
por: Jiang, Nan, et al.
Publicado: (2020)

WISARD: workbench for integrated superfast association studies for related datasets
por: Lee, Sungyoung, et al.
Publicado: (2018)

Network Graph Analysis of Gene-Gene Interactions in Genome-Wide Association Study Data
por: Lee, Sungyoung, et al.
Publicado: (2012)

CARAT-GxG: CUDA-Accelerated Regression Analysis Toolkit for Large-Scale Gene–Gene Interaction with GPU Computing System
por: Lee, Sungyoung, et al.
Publicado: (2014)

Ascertainment bias from imputation methods evaluation in wheat
por: Brandariz, Sofía P., et al.
Publicado: (2016)

Resolving kangaroo phylogeny and overcoming retrotransposon ascertainment bias
por: Dodt, William G., et al.
Publicado: (2017)

How array design creates SNP ascertainment bias
por: Geibel, Johannes, et al.
Publicado: (2021)

How imputation can mitigate SNP ascertainment Bias
por: Geibel, Johannes, et al.
Publicado: (2021)

Pathway-based approach using hierarchical components of rare variants to analyze multiple phenotypes
por: Lee, Sungyoung, et al.
Publicado: (2018)

HisCoM-G×E: Hierarchical Structural Component Analysis of Gene-Based Gene–Environment Interactions
por: Choi, Sungkyoung, et al.
Publicado: (2020)

Identifying miRNA-mRNA Integration Set Associated With Survival Time
por: Kim, Yongkang, et al.
Publicado: (2021)

Ascertainment Bias in Anaphylaxis Safety Data of COVID-19 Vaccines
por: Hourihane, Jonathan O’B., et al.
Publicado: (2021)

Ascertainment bias in the genomic test of positive selection on regulatory sequences
por: Jiang, Daohan, et al.
Publicado: (2023)

Hierarchical structural component modeling of microRNA-mRNA integration analysis
por: Kim, Yongkang, et al.
Publicado: (2018)

Detecting and Removing Ascertainment Bias in Microsatellites from the HGDP-CEPH Panel
por: Eriksson, Anders, et al.
Publicado: (2011)

Role of Ascertainment Bias in Determining Case Fatality Rate of COVID-19
por: Smith, Maia P.
Publicado: (2021)

Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis
por: Lee, Sungyoung, et al.
Publicado: (2019)

Item-level psychometrics of the Ascertain Dementia Eight-Item Informant Questionnaire
por: Ham, Yeajin, et al.
Publicado: (2022)

Characterization and Validation of an “Acute Aerobic Exercise Load” as a Tool to Assess Antioxidative and Anti-inflammatory Nutrition in Healthy Subjects Using a Statistically Integrated Approach in a Comprehensive Clinical Trial
por: Kim, Youjin, et al.
Publicado: (2019)

Impact of Marker Ascertainment Bias on Genomic Selection Accuracy and Estimates of Genetic Diversity
por: Heslot, Nicolas, et al.
Publicado: (2013)

Ascertainment Bias in a Historic Cohort Study of Residents in an Asbestos Manufacturing Community
por: Wortzel, Jeremy D., et al.
Publicado: (2021)

HisCoM-PAGE: Hierarchical Structural Component Models for Pathway Analysis of Gene Expression Data
por: Mok, Lydia, et al.
Publicado: (2019)

LPEseq: Local-Pooled-Error Test for RNA Sequencing Experiments with a Small Number of Replicates
por: Gim, Jungsoo, et al.
Publicado: (2016)

Evaluation of Penalized and Nonpenalized Methods for Disease Prediction with Large-Scale Genetic Data
por: Won, Sungho, et al.
Publicado: (2015)

Appropriate Number of Observations to Determine Hand Hygiene Compliance Among Healthcare Workers
por: Yoon Park, Se, et al.
Publicado: (2021)

Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias
por: Didion, John P, et al.
Publicado: (2012)

Ascertainment Bias in TB Treatment Trials: Can Systematic Assessment of Objective Endpoints Solve It?
por: Mitnick, Carole D., et al.
Publicado: (2023)

National Trends in the Treatment of Ruptured Cerebral Aneurysms in Korea Using an Age-adjusted Method
por: Park, Hye Ran, et al.
Publicado: (2020)

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2
por: Prokopenko, Dmitry, et al.
Publicado: (2022)

Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal development
por: Prokopenko, Dmitry, et al.
Publicado: (2021)

Efficiency of different strategies to mitigate ascertainment bias when using SNP panels in diversity studies
por: Malomane, Dorcus Kholofelo, et al.
Publicado: (2018)

On the Means of Ascertaining Infanticide
Publicado: (1826)

Cannot write session to /tmp/vufind_sessions/sess_ivvpgkr7ij8oq3sq8jqc0mgkrj