Structure of a bacterial RNA polymerase holoenzyme open promoter complex

Initiation of transcription is a primary means for controlling gene expression. In bacteria, the RNA polymerase (RNAP) holoenzyme binds and unwinds promoter DNA, forming the transcription bubble of the open promoter complex (RPo). We have determined crystal structures, refined to 4.14 Å-resolution,...

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Detalles Bibliográficos
Autores principales: Bae, Brian, Feklistov, Andrey, Lass-Napiorkowska, Agnieszka, Landick, Robert, Darst, Seth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593229/
https://www.ncbi.nlm.nih.gov/pubmed/26349032
http://dx.doi.org/10.7554/eLife.08504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593229/
https://www.ncbi.nlm.nih.gov/pubmed/26349032
http://dx.doi.org/10.7554/eLife.08504

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