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Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013
Ixodes scapularis ticks, which transmit Borrelia burgdorferi, the causative agent of Lyme disease (LD), are endemic to at least 6 regions of Nova Scotia, Canada. To assess the epidemiology and prevalence of LD in Nova Scotia, we analyzed data from 329 persons with LD reported in Nova Scotia during 2...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Centers for Disease Control and Prevention
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593424/ https://www.ncbi.nlm.nih.gov/pubmed/26401788 http://dx.doi.org/10.3201/eid2110.141640 |
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author | Hatchette, Todd F. Johnston, B. Lynn Schleihauf, Emily Mask, Angela Haldane, David Drebot, Michael Baikie, Maureen Cole, Teri J. Fleming, Sarah Gould, Richard Lindsay, Robbin |
author_facet | Hatchette, Todd F. Johnston, B. Lynn Schleihauf, Emily Mask, Angela Haldane, David Drebot, Michael Baikie, Maureen Cole, Teri J. Fleming, Sarah Gould, Richard Lindsay, Robbin |
author_sort | Hatchette, Todd F. |
collection | PubMed |
description | Ixodes scapularis ticks, which transmit Borrelia burgdorferi, the causative agent of Lyme disease (LD), are endemic to at least 6 regions of Nova Scotia, Canada. To assess the epidemiology and prevalence of LD in Nova Scotia, we analyzed data from 329 persons with LD reported in Nova Scotia during 2002–2013. Most patients reported symptoms of early localized infection with rash (89.7%), influenza-like illness (69.6%), or both; clinician-diagnosed erythema migrans was documented for 53.2%. In a separate serosurvey, of 1,855 serum samples screened for antibodies to B. burgdorferi, 2 were borderline positive (both with an indeterminate IgG on Western blot), resulting in an estimated seroprevalence of 0.14% (95% CI 0.02%–0.51%). Although LD incidence in Nova Scotia has risen sharply since 2002 and is the highest in Canada (16/100,000 population in 2013), the estimated number of residents with evidence of infection is low, and risk is localized to currently identified LD-endemic regions. |
format | Online Article Text |
id | pubmed-4593424 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-45934242015-10-05 Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 Hatchette, Todd F. Johnston, B. Lynn Schleihauf, Emily Mask, Angela Haldane, David Drebot, Michael Baikie, Maureen Cole, Teri J. Fleming, Sarah Gould, Richard Lindsay, Robbin Emerg Infect Dis Research Ixodes scapularis ticks, which transmit Borrelia burgdorferi, the causative agent of Lyme disease (LD), are endemic to at least 6 regions of Nova Scotia, Canada. To assess the epidemiology and prevalence of LD in Nova Scotia, we analyzed data from 329 persons with LD reported in Nova Scotia during 2002–2013. Most patients reported symptoms of early localized infection with rash (89.7%), influenza-like illness (69.6%), or both; clinician-diagnosed erythema migrans was documented for 53.2%. In a separate serosurvey, of 1,855 serum samples screened for antibodies to B. burgdorferi, 2 were borderline positive (both with an indeterminate IgG on Western blot), resulting in an estimated seroprevalence of 0.14% (95% CI 0.02%–0.51%). Although LD incidence in Nova Scotia has risen sharply since 2002 and is the highest in Canada (16/100,000 population in 2013), the estimated number of residents with evidence of infection is low, and risk is localized to currently identified LD-endemic regions. Centers for Disease Control and Prevention 2015-10 /pmc/articles/PMC4593424/ /pubmed/26401788 http://dx.doi.org/10.3201/eid2110.141640 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Hatchette, Todd F. Johnston, B. Lynn Schleihauf, Emily Mask, Angela Haldane, David Drebot, Michael Baikie, Maureen Cole, Teri J. Fleming, Sarah Gould, Richard Lindsay, Robbin Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title | Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title_full | Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title_fullStr | Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title_full_unstemmed | Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title_short | Epidemiology of Lyme Disease, Nova Scotia, Canada, 2002–2013 |
title_sort | epidemiology of lyme disease, nova scotia, canada, 2002–2013 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593424/ https://www.ncbi.nlm.nih.gov/pubmed/26401788 http://dx.doi.org/10.3201/eid2110.141640 |
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