Cargando…

Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013

In South Korea, nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) began during 2013. Among 301 surveillance cases, 35 hospitalized case-patients in 25 areas were confirmed by using virologic testing, and 16 (46%) case-patients subsequently died. The SFTS cases occurred d...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Jaeseung, Kwon, Donghyok, Youn, Seung-Ki, Park, Ji-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593431/
https://www.ncbi.nlm.nih.gov/pubmed/26402575
http://dx.doi.org/10.3201/eid2110.141928
_version_ 1782393321595863040
author Shin, Jaeseung
Kwon, Donghyok
Youn, Seung-Ki
Park, Ji-Hyuk
author_facet Shin, Jaeseung
Kwon, Donghyok
Youn, Seung-Ki
Park, Ji-Hyuk
author_sort Shin, Jaeseung
collection PubMed
description In South Korea, nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) began during 2013. Among 301 surveillance cases, 35 hospitalized case-patients in 25 areas were confirmed by using virologic testing, and 16 (46%) case-patients subsequently died. The SFTS cases occurred during May–November and peaked during June (9 cases, 26%). The incidence of SFTS was higher in the southern regions of South Korea. Age and neurologic symptoms, including decreased level of consciousness and slurred speech, were heavily associated with death; neurologic symptoms during the first week after disease onset were also associated with death. Although melena was common among patients who died, no other hemorrhagic manifestations were substantively more common among those who died. No effective treatments, including ribavirin, were identified. Expansion of SFTS surveillance to include the outpatient sector and development of an antibody test would enhance completeness of SFTS detection in South Korea.
format Online
Article
Text
id pubmed-4593431
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-45934312015-10-05 Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013 Shin, Jaeseung Kwon, Donghyok Youn, Seung-Ki Park, Ji-Hyuk Emerg Infect Dis Synopsis In South Korea, nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) began during 2013. Among 301 surveillance cases, 35 hospitalized case-patients in 25 areas were confirmed by using virologic testing, and 16 (46%) case-patients subsequently died. The SFTS cases occurred during May–November and peaked during June (9 cases, 26%). The incidence of SFTS was higher in the southern regions of South Korea. Age and neurologic symptoms, including decreased level of consciousness and slurred speech, were heavily associated with death; neurologic symptoms during the first week after disease onset were also associated with death. Although melena was common among patients who died, no other hemorrhagic manifestations were substantively more common among those who died. No effective treatments, including ribavirin, were identified. Expansion of SFTS surveillance to include the outpatient sector and development of an antibody test would enhance completeness of SFTS detection in South Korea. Centers for Disease Control and Prevention 2015-10 /pmc/articles/PMC4593431/ /pubmed/26402575 http://dx.doi.org/10.3201/eid2110.141928 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Synopsis
Shin, Jaeseung
Kwon, Donghyok
Youn, Seung-Ki
Park, Ji-Hyuk
Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title_full Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title_fullStr Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title_full_unstemmed Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title_short Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013
title_sort characteristics and factors associated with death among patients hospitalized for severe fever with thrombocytopenia syndrome, south korea, 2013
topic Synopsis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593431/
https://www.ncbi.nlm.nih.gov/pubmed/26402575
http://dx.doi.org/10.3201/eid2110.141928
work_keys_str_mv AT shinjaeseung characteristicsandfactorsassociatedwithdeathamongpatientshospitalizedforseverefeverwiththrombocytopeniasyndromesouthkorea2013
AT kwondonghyok characteristicsandfactorsassociatedwithdeathamongpatientshospitalizedforseverefeverwiththrombocytopeniasyndromesouthkorea2013
AT younseungki characteristicsandfactorsassociatedwithdeathamongpatientshospitalizedforseverefeverwiththrombocytopeniasyndromesouthkorea2013
AT parkjihyuk characteristicsandfactorsassociatedwithdeathamongpatientshospitalizedforseverefeverwiththrombocytopeniasyndromesouthkorea2013