Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellen...

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Autores principales: Spengler, Jessica R., Chakrabarti, Ayan K., Coleman-McCray, JoAnn D., Martin, Brock E., Nichol, Stuart T., Spiropoulou, Christina F., Bird, Brian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2015
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593453/
https://www.ncbi.nlm.nih.gov/pubmed/26401603
http://dx.doi.org/10.3201/eid2110.150840
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author Spengler, Jessica R.
Chakrabarti, Ayan K.
Coleman-McCray, JoAnn D.
Martin, Brock E.
Nichol, Stuart T.
Spiropoulou, Christina F.
Bird, Brian H.
author_facet Spengler, Jessica R.
Chakrabarti, Ayan K.
Coleman-McCray, JoAnn D.
Martin, Brock E.
Nichol, Stuart T.
Spiropoulou, Christina F.
Bird, Brian H.
author_sort Spengler, Jessica R.
collection PubMed
description To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples.
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spelling pubmed-45934532015-10-05 Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model Spengler, Jessica R. Chakrabarti, Ayan K. Coleman-McCray, JoAnn D. Martin, Brock E. Nichol, Stuart T. Spiropoulou, Christina F. Bird, Brian H. Emerg Infect Dis Dispatch To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples. Centers for Disease Control and Prevention 2015-10 /pmc/articles/PMC4593453/ /pubmed/26401603 http://dx.doi.org/10.3201/eid2110.150840 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Spengler, Jessica R.
Chakrabarti, Ayan K.
Coleman-McCray, JoAnn D.
Martin, Brock E.
Nichol, Stuart T.
Spiropoulou, Christina F.
Bird, Brian H.
Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title_full Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title_fullStr Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title_full_unstemmed Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title_short Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model
title_sort utility of oral swab sampling for ebola virus detection in guinea pig model
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593453/
https://www.ncbi.nlm.nih.gov/pubmed/26401603
http://dx.doi.org/10.3201/eid2110.150840
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