The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage

Metnase (also known as SETMAR) is a chimeric SET-transposase protein that plays essential role(s) in non-homologous end joining (NHEJ) repair and replication fork restart. Although the SET domain possesses histone H3 lysine 36 dimethylation (H3K36me2) activity associated with an improved association...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Suk, Kim, Sung-Kyung, Hromas, Robert, Lee, Suk-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593633/
https://www.ncbi.nlm.nih.gov/pubmed/26437079
http://dx.doi.org/10.1371/journal.pone.0139418

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