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Predicting Neuroinflammation in Morphine Tolerance for Tolerance Therapy from Immunostaining Images of Rat Spinal Cord
Long-term morphine treatment leads to tolerance which attenuates analgesic effect and hampers clinical utilization. Recent studies have sought to reveal the mechanism of opioid receptors and neuroinflammation by observing morphological changes of cells in the rat spinal cord. This work proposes a hi...
Autores principales: | Lin, Shinn-Long, Chang, Fang-Lin, Ho, Shinn-Ying, Charoenkwan, Phasit, Wang, Kuan-Wei, Huang, Hui-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593634/ https://www.ncbi.nlm.nih.gov/pubmed/26437460 http://dx.doi.org/10.1371/journal.pone.0139806 |
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