Reduced Gut Acidity Induces an Obese-Like Phenotype in Drosophila melanogaster and in Mice

In order to identify genes involved in stress and metabolic regulation, we carried out a Drosophila P-element-mediated mutagenesis screen for starvation resistance. We isolated a mutant, m2, that showed a 23% increase in survival time under starvation conditions. The P-element insertion was mapped t...

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Detalles Bibliográficos
Autores principales: Lin, Wei-Sheng, Huang, Cheng-Wen, Song, You-Sheng, Yen, Jui-Hung, Kuo, Ping-Chang, Yeh, Sheng-Rong, Lin, Hung-Yu, Fu, Tsai-Feng, Wu, Ming-Shiang, Wang, Horng-Dar, Wang, Pei-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593636/
https://www.ncbi.nlm.nih.gov/pubmed/26436771
http://dx.doi.org/10.1371/journal.pone.0139722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593636/
https://www.ncbi.nlm.nih.gov/pubmed/26436771
http://dx.doi.org/10.1371/journal.pone.0139722

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