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Reduced Gut Acidity Induces an Obese-Like Phenotype in Drosophila melanogaster and in Mice
In order to identify genes involved in stress and metabolic regulation, we carried out a Drosophila P-element-mediated mutagenesis screen for starvation resistance. We isolated a mutant, m2, that showed a 23% increase in survival time under starvation conditions. The P-element insertion was mapped t...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593636/ https://www.ncbi.nlm.nih.gov/pubmed/26436771 http://dx.doi.org/10.1371/journal.pone.0139722 |