Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

BACKGROUND: Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD). We used UK Biobank data to study the genetic causes of smoking behaviour and lung health. METHODS: We sampled individual...

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Detalles Bibliográficos
Autores principales: Wain, Louise V, Shrine, Nick, Miller, Suzanne, Jackson, Victoria E, Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K, Kheirallah, Abdul Kader, Allen, Richard, Cook, James P, Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S, Paré, Peter D, Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L, Thomson, Neil C, Zeggini, Eleftheria, Morris, Andrew P, Marchini, Jonathan, Strachan, David P, Tobin, Martin D, Hall, Ian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593935/
https://www.ncbi.nlm.nih.gov/pubmed/26423011
http://dx.doi.org/10.1016/S2213-2600(15)00283-0

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