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Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients

Adaptive natural killer (NK) cell responses to human cytomegalovirus infection are characterized by the expansion of NKG2C(+) NK cells expressing self-specific inhibitory killer-cell immunoglobulin-like receptors (KIRs). Here, we set out to study the HLA class I dependency of such NKG2C(+) NK cell e...

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Detalles Bibliográficos
Autores principales: Béziat, Vivien, Sleiman, Marwan, Goodridge, Jodie P., Kaarbø, Mari, Liu, Lisa L., Rollag, Halvor, Ljunggren, Hans-Gustaf, Zimmer, Jacques, Malmberg, Karl-Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594010/
https://www.ncbi.nlm.nih.gov/pubmed/26500647
http://dx.doi.org/10.3389/fimmu.2015.00507