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Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides

Multifunctional nanoparticles exhibiting red or green luminescence properties and magnetism were synthesized and thoroughly analyzed. The hydrothermal method was used for the synthesis of Eu(3+)- or Tb(3+)-doped GdF(3)-, NaGdF(4)-, and BaGdF(5)-based nanocrystalline materials. The X-ray diffraction...

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Autores principales: Grzyb, Tomasz, Mrówczyńska, Lucyna, Szczeszak, Agata, Śniadecki, Zbigniew, Runowski, Marcin, Idzikowski, Bogdan, Lis, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594090/
https://www.ncbi.nlm.nih.gov/pubmed/26457061
http://dx.doi.org/10.1007/s11051-015-3191-2
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author Grzyb, Tomasz
Mrówczyńska, Lucyna
Szczeszak, Agata
Śniadecki, Zbigniew
Runowski, Marcin
Idzikowski, Bogdan
Lis, Stefan
author_facet Grzyb, Tomasz
Mrówczyńska, Lucyna
Szczeszak, Agata
Śniadecki, Zbigniew
Runowski, Marcin
Idzikowski, Bogdan
Lis, Stefan
author_sort Grzyb, Tomasz
collection PubMed
description Multifunctional nanoparticles exhibiting red or green luminescence properties and magnetism were synthesized and thoroughly analyzed. The hydrothermal method was used for the synthesis of Eu(3+)- or Tb(3+)-doped GdF(3)-, NaGdF(4)-, and BaGdF(5)-based nanocrystalline materials. The X-ray diffraction patterns of the samples confirmed the desired compositions of the materials. Transmission electron microscope images revealed the different morphologies of the products, including the nanocrystal sizes, which varied from 12 nm in the case of BaGdF(5)-based nanoparticles to larger structures with dimensions exceeding 300 nm. All of the samples presented luminescence under ultraviolet irradiation, as well as when the samples were in the form of water colloids. The highest luminescence was observed for BaGdF(5)-based materials. The obtained nanoparticles exhibited paramagnetism along with probable evidence of superparamagnetic behavior at low temperatures. The particles’ magnetic characteristics were also preserved for samples in the form of a suspension in distilled water. The cytotoxicity studies against the human erythrocytes indicated that the synthesized nanoparticles are non-toxic because they did not cause the red blood cells shape changes nor did they alter their membrane structure and permeabilization. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11051-015-3191-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-45940902015-10-09 Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides Grzyb, Tomasz Mrówczyńska, Lucyna Szczeszak, Agata Śniadecki, Zbigniew Runowski, Marcin Idzikowski, Bogdan Lis, Stefan J Nanopart Res Research Paper Multifunctional nanoparticles exhibiting red or green luminescence properties and magnetism were synthesized and thoroughly analyzed. The hydrothermal method was used for the synthesis of Eu(3+)- or Tb(3+)-doped GdF(3)-, NaGdF(4)-, and BaGdF(5)-based nanocrystalline materials. The X-ray diffraction patterns of the samples confirmed the desired compositions of the materials. Transmission electron microscope images revealed the different morphologies of the products, including the nanocrystal sizes, which varied from 12 nm in the case of BaGdF(5)-based nanoparticles to larger structures with dimensions exceeding 300 nm. All of the samples presented luminescence under ultraviolet irradiation, as well as when the samples were in the form of water colloids. The highest luminescence was observed for BaGdF(5)-based materials. The obtained nanoparticles exhibited paramagnetism along with probable evidence of superparamagnetic behavior at low temperatures. The particles’ magnetic characteristics were also preserved for samples in the form of a suspension in distilled water. The cytotoxicity studies against the human erythrocytes indicated that the synthesized nanoparticles are non-toxic because they did not cause the red blood cells shape changes nor did they alter their membrane structure and permeabilization. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11051-015-3191-2) contains supplementary material, which is available to authorized users. Springer Netherlands 2015-10-05 2015 /pmc/articles/PMC4594090/ /pubmed/26457061 http://dx.doi.org/10.1007/s11051-015-3191-2 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research Paper
Grzyb, Tomasz
Mrówczyńska, Lucyna
Szczeszak, Agata
Śniadecki, Zbigniew
Runowski, Marcin
Idzikowski, Bogdan
Lis, Stefan
Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title_full Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title_fullStr Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title_full_unstemmed Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title_short Synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
title_sort synthesis, characterization, and cytotoxicity in human erythrocytes of multifunctional, magnetic, and luminescent nanocrystalline rare earth fluorides
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594090/
https://www.ncbi.nlm.nih.gov/pubmed/26457061
http://dx.doi.org/10.1007/s11051-015-3191-2
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