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High resolution structure of an M23 peptidase with a substrate analogue
LytM is a Staphylococcus aureus autolysin and a homologue of the S. simulans lysostaphin. Both enzymes are members of M23 metallopeptidase family (MEROPS) comprising primarily bacterial peptidoglycan hydrolases. LytM occurs naturally in a latent form, but can be activated by cleavage of an inhibitor...
Autores principales: | Grabowska, Maja, Jagielska, Elzbieta, Czapinska, Honorata, Bochtler, Matthias, Sabala, Izabela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594094/ https://www.ncbi.nlm.nih.gov/pubmed/26437833 http://dx.doi.org/10.1038/srep14833 |
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