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Cytosolically expressed PrP GPI-signal peptide interacts with mitochondria

We previously reported that PrP GPI-anchor signal peptide (GPI-SP) is specifically degraded by the proteasome. Additionally, we showed that the point mutation P238S, responsible for a genetic form of prion diseases, while not affecting the GPI-anchoring process, results in the accumulation of PrP GP...

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Detalles Bibliográficos
Autores principales:	Guizzunti, Gianni, Zurzolo, Chiara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Article Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594234/ https://www.ncbi.nlm.nih.gov/pubmed/26480298 http://dx.doi.org/10.1080/19420889.2015.1036206

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