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Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

Several recent ion channel structures have revealed large side portals, or ‘fenestrations’ at the interface between their transmembrane helices that potentially expose the ion conduction pathway to the lipid core of the bilayer. In a recent study we demonstrated that functional activity of the TWIK-...

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Detalles Bibliográficos
Autores principales:	Aryal, Prafulla, Abd-Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark SP, Tucker, Stephen J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Article Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594343/ https://www.ncbi.nlm.nih.gov/pubmed/25487004 http://dx.doi.org/10.4161/19336950.2014.981987

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