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Translational regulation of the expression of the ubiquitin E3 ligase Nedd4–1 by mTORC1-dependent signaling
We found recently that mTORC1 regulates the biosynthesis of the ubiquitin E3 ligase Nedd4–1, but not the close homolog Nedd4–2. This regulatory process plays a key role in promoting neurite growth in neurons of the mammalian central nervous system. The molecular mechanism underlying this rather spec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594434/ https://www.ncbi.nlm.nih.gov/pubmed/26479408 http://dx.doi.org/10.1080/19420889.2015.1017161 |