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Decrease of gene expression of astrocytic 5-HT(2B) receptors parallels development of depressive phenotype in a mouse model of Parkinson’s disease
Astrocytes contribute to pathogenesis of neuropsychiatric disorders, including major depression. Stimulation of astroglial 5-HT(2B) receptors transactivates epidermal growth factor receptors (EGFRs) and regulates gene expression. Previously we reported that expression of 5-HT(2B) receptors in cortic...
Autores principales: | Zhang, Xique, Song, Dan, Gu, Li, Ren, Yan, Verkhratsky, Alexei, Peng, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594497/ https://www.ncbi.nlm.nih.gov/pubmed/26500493 http://dx.doi.org/10.3389/fncel.2015.00388 |
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