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Why so many sperm cells?

A key limiting step in fertility is the search for the oocyte by spermatozoa. Initially, there are tens of millions of sperm cells, but a single one will make it to the oocyte. This may be one of the most severe selection processes designed by evolution, whose role is yet to be understood. Why such...

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Detalles Bibliográficos
Autores principales: Reynaud, Karine, Schuss, Zeev, Rouach, Nathalie, Holcman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594528/
https://www.ncbi.nlm.nih.gov/pubmed/26478772
http://dx.doi.org/10.1080/19420889.2015.1017156
Descripción
Sumario:A key limiting step in fertility is the search for the oocyte by spermatozoa. Initially, there are tens of millions of sperm cells, but a single one will make it to the oocyte. This may be one of the most severe selection processes designed by evolution, whose role is yet to be understood. Why such a huge redundancy is required and what does that mean for the search process? we discuss here these questions and consequently new lines of interdisciplinary research needed to find possible answers.