Cargando…

A molecular understanding of d-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells

2-Methoxyestradiol (ME), one of the most widely investigated A-ring-modified metabolites of estrone, exerts significant anticancer activity on numerous cancer cell lines. Its pharmacological actions, including cell cycle arrest, microtubule disruption and pro-apoptotic activity, have already been de...

Descripción completa

Detalles Bibliográficos
Autores principales:	Minorics, Renáta, Bózsity, Noémi, Molnár, Judit, Wölfling, János, Mernyák, Erzsébet, Schneider, Gyula, Ocsovszki, Imre, Zupkó, István
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594678/ https://www.ncbi.nlm.nih.gov/pubmed/26228523 http://dx.doi.org/10.1111/jcmm.12587

Ejemplares similares

Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-d-Secoestrone Alcohols: The First Potent 13α-d-Secoestrone Derivative
por: Szabó, Johanna, et al.
Publicado: (2016)

A Click Approach to Novel D-Ring-Substituted 16α-Triazolylestrone Derivatives and Characterization of Their Antiproliferative Properties
por: Molnár, Judit, et al.
Publicado: (2015)

Antiproliferative Properties of Newly Synthesized 19-Nortestosterone Analogs Without Substantial Androgenic Activity
por: Gyovai, András, et al.
Publicado: (2018)

Anticancer and Multidrug Resistance-Reversal Effects of Solanidine Analogs Synthetized from Pregnadienolone Acetate
por: Zupkó, István, et al.
Publicado: (2014)

Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates
por: Bodnár, Brigitta, et al.
Publicado: (2016)

Investigation of the Antineoplastic Effects of 2-(4-Chlorophenyl)-13α-Estrone Sulfamate against the HPV16-Positive Human Invasive Cervical Carcinoma Cell Line SiHa
por: Ali, Hazhmat, et al.
Publicado: (2023)

Synthesis and Antiproliferative Activity of Steroidal Diaryl Ethers
por: Kovács, Édua, et al.
Publicado: (2023)

Synthesis and evaluation of anticancer activities of 2- or 4-substituted 3-(N-benzyltriazolylmethyl)-13α-oestrone derivatives
por: Jójárt, Rebeka, et al.
Publicado: (2020)

The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series
por: Bacsa, Ildikó, et al.
Publicado: (2018)

Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1
por: Herman, Bianka Edina, et al.
Publicado: (2019)

Microwave-assisted Phospha-Michael addition reactions in the 13α-oestrone series and in vitro antiproliferative properties
por: Mernyák, Erzsébet, et al.
Publicado: (2021)

Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-O-Benzyl Estrone Analogs †
por: Senobar Tahaei, Seyyed Ashkan, et al.
Publicado: (2023)

Synthesis of novel 13α-estrone derivatives by Sonogashira coupling as potential 17β-HSD1 inhibitors
por: Bacsa, Ildikó, et al.
Publicado: (2017)

Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro
por: Molnár, Judit, et al.
Publicado: (2016)

Synthesis and In Vitro Antiproliferative Activity of Novel Androst-5-ene Triazolyl and Tetrazolyl Derivatives
por: Kádár, Zalán, et al.
Publicado: (2011)

Isolation, Structure Determination of Sesquiterpenes from Neurolaena lobata and Their Antiproliferative, Cell Cycle Arrest-Inducing and Anti-Invasive Properties against Human Cervical Tumor Cells
por: Vasas, Andrea, et al.
Publicado: (2021)

Cellular Effects of Cyclodextrins: Studies on HeLa Cells
por: Rusznyák, Ágnes, et al.
Publicado: (2022)

Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells
por: Stefanowicz-Hajduk, Justyna, et al.
Publicado: (2016)

Ivermectin induces cell cycle arrest and apoptosis of HeLa cells via mitochondrial pathway
por: Zhang, Ping, et al.
Publicado: (2018)

Electrolyte Metabolism in HeLa Cells
por: Wickson-ginzburg, Margaret, et al.
Publicado: (1963)

Editorial: HeLa Cell Sequela
Publicado: (2013)

The fractured genome of HeLa cells
por: Mittelman, David, et al.
Publicado: (2013)

Induction of Apoptotic Death and Cell Cycle Arrest in HeLa Cells by Extracellular Factors of Breast Cancer Cells
por: Jahagirdar, Devashree, et al.
Publicado: (2018)

On the dynamics of the microfilament system in HeLa cells
por: Blikstad, I, et al.
Publicado: (1982)

Microtubule-associated proteins of HeLa cells: heat stability of the 200,000 mol wt HeLa MAPs and detection of the presence of MAP-2 in HeLa cell extracts and cycled microtubules
Publicado: (1982)

Toona Sinensis and Moschus Decoction Induced Cell Cycle Arrest in Human Cervical Carcinoma HeLa Cells
por: Zhen, Hong, et al.
Publicado: (2014)

Nickel nanowires induce cell cycle arrest and apoptosis by generation of reactive oxygen species in HeLa cells
por: Ma, ChangGuo, et al.
Publicado: (2014)

Xanthohumol-Enriched Beer Does Not Exert Antitumorigenic Effects on HeLa Cell Line In Vivo
por: Éliás, Anna Júlia, et al.
Publicado: (2023)

Effect of SP600125 on the mitotic spindle in HeLa Cells, leading to mitotic arrest, endoreduplication and apoptosis
por: Mili, Donia, et al.
Publicado: (2016)

NUP210 and MicroRNA-22 Modulate Fas to Elicit HeLa Cell Cycle Arrest
por: Gu, Qiao, et al.
Publicado: (2020)

C1 Domain-Targeted Isophthalate Derivatives Induce Cell Elongation and Cell Cycle Arrest in HeLa Cells
por: Talman, Virpi, et al.
Publicado: (2011)

Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis
por: Bacsa, Ildikó, et al.
Publicado: (2018)

Poly A- Transcripts Expressed in HeLa Cells
por: Wu, Qingfa, et al.
Publicado: (2008)

Hyperthermia and the heat-shock proteins of HeLa cells.
por: Burdon, R. H., et al.
Publicado: (1982)

In vitro polymerization of microtubules from HeLa cells
Publicado: (1978)

Transport and topology of galactosyltransferase in endomembranes of HeLa cells
Publicado: (1983)

Evidence for the autophagy of microinjected proteins in HeLA cells
Publicado: (1977)

Autophagy Facilitates Salmonella Replication in HeLa Cells
por: Yu, Hong B., et al.
Publicado: (2014)

Dynamic influence of Rhein lysinate on HeLa cells
por: Liu, Jiang, et al.
Publicado: (2018)

Evaluation of Ectopic Mitochondrial DNA in HeLa Cells
por: Hussan, Mohammad T., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_f07fmbchtdsg0to0ttq62o2l50