Cargando…
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model
BACKGROUND: Pigs (Sus scrofa) provide relevant biomedical models to dissect complex diseases due to their anatomical, genetic, and physiological similarities with humans. Aberrant DNA methylation has been linked to many of these diseases and is associated with gene expression; however, the functiona...
Autores principales: | Schachtschneider, Kyle M., Madsen, Ole, Park, Chankyu, Rund, Laurie A., Groenen, Martien A. M., Schook, Lawrence B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594891/ https://www.ncbi.nlm.nih.gov/pubmed/26438392 http://dx.doi.org/10.1186/s12864-015-1938-x |
Ejemplares similares
-
Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development
por: Schachtschneider, Kyle M., et al.
Publicado: (2016) -
Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas
por: Schachtschneider, Kyle M., et al.
Publicado: (2017) -
Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults
por: Schachtschneider, Kyle M., et al.
Publicado: (2020) -
Creating Porcine Biomedical Models Through Recombineering
por: Rogatcheva, Margarita M., et al.
Publicado: (2004) -
Translating Human Cancer Sequences Into Personalized Porcine Cancer Models
por: Xu, Chunlong, et al.
Publicado: (2019)