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BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAM(low) CD11b(high) Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming
The transport of antigen from the periphery to the draining lymph node (DLN) is critical for T-cell priming but remains poorly studied during infection with Mycobacterium bovis Bacille Calmette-Guérin (BCG). To address this we employed a mouse model to track the traffic of Dendritic cells (DCs) and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594926/ https://www.ncbi.nlm.nih.gov/pubmed/26440518 http://dx.doi.org/10.1371/journal.ppat.1005206 |