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BCG Skin Infection Triggers IL-1R-MyD88-Dependent Migration of EpCAM(low) CD11b(high) Skin Dendritic cells to Draining Lymph Node During CD4+ T-Cell Priming

The transport of antigen from the periphery to the draining lymph node (DLN) is critical for T-cell priming but remains poorly studied during infection with Mycobacterium bovis Bacille Calmette-Guérin (BCG). To address this we employed a mouse model to track the traffic of Dendritic cells (DCs) and...

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Detalles Bibliográficos
Autores principales: Bollampalli, Vishnu Priya, Harumi Yamashiro, Lívia, Feng, Xiaogang, Bierschenk, Damiën, Gao, Yu, Blom, Hans, Henriques-Normark, Birgitta, Nylén, Susanne, Rothfuchs, Antonio Gigliotti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594926/
https://www.ncbi.nlm.nih.gov/pubmed/26440518
http://dx.doi.org/10.1371/journal.ppat.1005206

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