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A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18–40 Year Old Subjects with Diagnosed Atopic Dermatitis
BACKGROUND: Replicating smallpox vaccines can cause severe complications in individuals with atopic dermatitis (AD). Prior studies evaluating Modified Vaccinia Ankara virus (MVA), a non-replicating vaccine in humans, showed a favorable safety and immunogenicity profile in healthy volunteers. OBJECTI...
Autores principales: | Greenberg, Richard N, Hurley, Yadira, Dinh, Dinh V., Mraz, Serena, Vera, Javier Gomez, von Bredow, Dorothea, von Krempelhuber, Alfred, Roesch, Siegfried, Virgin, Garth, Arndtz-Wiedemann, Nathaly, Meyer, Thomas Peter, Schmidt, Darja, Nichols, Richard, Young, Philip, Chaplin, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595076/ https://www.ncbi.nlm.nih.gov/pubmed/26439129 http://dx.doi.org/10.1371/journal.pone.0138348 |
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