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Linear atrophoderma of Moulin: an underrecognized entity

Linear atrophoderma of Moulin (LAM) is an acquired skin condition that manifests in early childhood and adolescence. It likely represents a form of cutaneous mosaicism that presents with linear, hyperpigmented and atrophic lesions appearing on the trunk and limbs. Its clinical appearance varies and...

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Autores principales: Zahedi niaki, Omid, Sissons, Wendy, Nguyen, Van-Hung, Zargham, Ramin, Jafarian, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595104/
https://www.ncbi.nlm.nih.gov/pubmed/26438123
http://dx.doi.org/10.1186/s12969-015-0036-6
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author Zahedi niaki, Omid
Sissons, Wendy
Nguyen, Van-Hung
Zargham, Ramin
Jafarian, Fatemeh
author_facet Zahedi niaki, Omid
Sissons, Wendy
Nguyen, Van-Hung
Zargham, Ramin
Jafarian, Fatemeh
author_sort Zahedi niaki, Omid
collection PubMed
description Linear atrophoderma of Moulin (LAM) is an acquired skin condition that manifests in early childhood and adolescence. It likely represents a form of cutaneous mosaicism that presents with linear, hyperpigmented and atrophic lesions appearing on the trunk and limbs. Its clinical appearance varies and may closely resemble that of atrophoderma of Pasini and Pierini (APP) and linear scleroderma. LAM usually follows a benign course and no effective treatment options exist. We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years. The initial clinical impression of linear scleroderma was reviewed in favor of LAM following histological examination of the lesions which revealed no significant inflammatory changes. LAM remains a rare and possibly under recognized entity with reports confined only to the dermatologic literature. This case highlights the importance of recognizing LAM and distinguishing it from linear scleroderma given the significant differences in management and prognosis.
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spelling pubmed-45951042015-10-07 Linear atrophoderma of Moulin: an underrecognized entity Zahedi niaki, Omid Sissons, Wendy Nguyen, Van-Hung Zargham, Ramin Jafarian, Fatemeh Pediatr Rheumatol Online J Case Report Linear atrophoderma of Moulin (LAM) is an acquired skin condition that manifests in early childhood and adolescence. It likely represents a form of cutaneous mosaicism that presents with linear, hyperpigmented and atrophic lesions appearing on the trunk and limbs. Its clinical appearance varies and may closely resemble that of atrophoderma of Pasini and Pierini (APP) and linear scleroderma. LAM usually follows a benign course and no effective treatment options exist. We present a case of a young and healthy patient that developed such lesions on her upper and lower extremities over 5 years. The initial clinical impression of linear scleroderma was reviewed in favor of LAM following histological examination of the lesions which revealed no significant inflammatory changes. LAM remains a rare and possibly under recognized entity with reports confined only to the dermatologic literature. This case highlights the importance of recognizing LAM and distinguishing it from linear scleroderma given the significant differences in management and prognosis. BioMed Central 2015-10-06 /pmc/articles/PMC4595104/ /pubmed/26438123 http://dx.doi.org/10.1186/s12969-015-0036-6 Text en © Zahedi niaki et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Zahedi niaki, Omid
Sissons, Wendy
Nguyen, Van-Hung
Zargham, Ramin
Jafarian, Fatemeh
Linear atrophoderma of Moulin: an underrecognized entity
title Linear atrophoderma of Moulin: an underrecognized entity
title_full Linear atrophoderma of Moulin: an underrecognized entity
title_fullStr Linear atrophoderma of Moulin: an underrecognized entity
title_full_unstemmed Linear atrophoderma of Moulin: an underrecognized entity
title_short Linear atrophoderma of Moulin: an underrecognized entity
title_sort linear atrophoderma of moulin: an underrecognized entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595104/
https://www.ncbi.nlm.nih.gov/pubmed/26438123
http://dx.doi.org/10.1186/s12969-015-0036-6
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