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Towards in vivo estimation of reaction kinetics using high-throughput metabolomics data: a maximum likelihood approach

BACKGROUND: High-throughput assays such as mass spectrometry have opened up the possibility for large-scale in vivo measurements of the metabolome. This data could potentially be used to estimate kinetic parameters for many metabolic reactions. However, high-throughput in vivo measurements have spec...

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Detalles Bibliográficos
Autores principales: Zhang, Weiruo, Kolte, Ritesh, Dill, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595320/
https://www.ncbi.nlm.nih.gov/pubmed/26437964
http://dx.doi.org/10.1186/s12918-015-0214-7