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Towards in vivo estimation of reaction kinetics using high-throughput metabolomics data: a maximum likelihood approach
BACKGROUND: High-throughput assays such as mass spectrometry have opened up the possibility for large-scale in vivo measurements of the metabolome. This data could potentially be used to estimate kinetic parameters for many metabolic reactions. However, high-throughput in vivo measurements have spec...
Autores principales: | Zhang, Weiruo, Kolte, Ritesh, Dill, David L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595320/ https://www.ncbi.nlm.nih.gov/pubmed/26437964 http://dx.doi.org/10.1186/s12918-015-0214-7 |
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