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Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription

BACKGROUND: Hes6 is a transcriptional regulator that induces transcriptional activation by binding to transcription repressor Hes1 and suppressing its activity. Hes6 is controlled by the ubiquitin-proteosome-mediated degradation system. Here we investigated the sumoylation of Hes6 and its functional...

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Detalles Bibliográficos
Autores principales:	Lee, Jiwon, Chun, Sung Kook, Son, Gi Hoon, Kim, Kyungjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Endocrine Society 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595364/ https://www.ncbi.nlm.nih.gov/pubmed/26435136 http://dx.doi.org/10.3803/EnM.2015.30.3.381

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