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Intermittent Administration of Parathyroid Hormone [1–34] Prevents Particle-Induced Periprosthetic Osteolysis in a Rat Model

We examined whether intermittent administration of parathyroid hormone [1–34] (PTH[1–34]; 60 μg/kg/day) can prevent the negative effects of titanium (Ti) particles on implant fixation and periprosthetic osteolysis in a rat model. Eighteen adult male rats (12 weeks old, bones still growing) received...

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Detalles Bibliográficos
Autores principales: Bi, Fanggang, Shi, Zhongli, Zhou, Chenhe, Liu, An, Shen, Yue, Yan, Shigui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595472/
https://www.ncbi.nlm.nih.gov/pubmed/26441073
http://dx.doi.org/10.1371/journal.pone.0139793