EP4 Receptor–Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis

Prostaglandin E(2) plays important roles in the maintenance of colonic homeostasis. The recently identified prostaglandin E receptor (EP) 4–associated protein (EPRAP) is essential for an anti-inflammatory function of EP4 signaling in macrophages in vitro. To investigate the in vivo roles of EPRAP, w...

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Detalles Bibliográficos
Autores principales: Nakatsuji, Masato, Minami, Manabu, Seno, Hiroshi, Yasui, Mika, Komekado, Hideyuki, Higuchi, Sei, Fujikawa, Risako, Nakanishi, Yuki, Fukuda, Akihisa, Kawada, Kenji, Sakai, Yoshiharu, Kita, Toru, Libby, Peter, Ikeuchi, Hiroki, Yokode, Masayuki, Chiba, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595503/
https://www.ncbi.nlm.nih.gov/pubmed/26439841
http://dx.doi.org/10.1371/journal.pgen.1005542

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