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ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection
BACKGROUND/OBJECTIVE: Genetic polymorphisms in the inosine triphosphatase (ITPA) gene have been associated with the protection from early ribavirin(RBV)-induced hemolytic anemia among patients with chronic hepatitis C virus (HCV) infection. The aim of the present study was to investigate the associa...
Autores principales: | Maan, Raoel, van der Meer, Adriaan J., Brouwer, Willem Pieter, Plompen, Elisabeth P. C., Sonneveld, Milan J., Roomer, Robert, van der Eijk, Annemiek A., Groothuismink, Zwier M. A., Hansen, Bettina E., Veldt, Bart J., Janssen, Harry L. A., Boonstra, Andre, de Knegt, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595504/ https://www.ncbi.nlm.nih.gov/pubmed/26441325 http://dx.doi.org/10.1371/journal.pone.0139317 |
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