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Computational reconstitution of spine calcium transients from individual proteins
We have built a stochastic model in the program MCell that simulates Ca(2+) transients in spines from the principal molecular components believed to control Ca(2+) entry and exit. Proteins, with their kinetic models, are located within two segments of dendrites containing 88 intact spines, centered...
Autores principales: | Bartol, Thomas M., Keller, Daniel X., Kinney, Justin P., Bajaj, Chandrajit L., Harris, Kristen M., Sejnowski, Terrence J., Kennedy, Mary B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595661/ https://www.ncbi.nlm.nih.gov/pubmed/26500546 http://dx.doi.org/10.3389/fnsyn.2015.00017 |
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