Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation

Embryonic stem cell (ESC) culture conditions are important for maintaining long-term self-renewal, and they influence cellular pluripotency state. Here, we report single cell RNA-sequencing of mESCs cultured in three different conditions: serum, 2i, and the alternative ground state a2i. We find that...

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Detalles Bibliográficos
Autores principales: Kolodziejczyk, Aleksandra A., Kim, Jong Kyoung, Tsang, Jason C.H., Ilicic, Tomislav, Henriksson, Johan, Natarajan, Kedar N., Tuck, Alex C., Gao, Xuefei, Bühler, Marc, Liu, Pentao, Marioni, John C., Teichmann, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595712/
https://www.ncbi.nlm.nih.gov/pubmed/26431182
http://dx.doi.org/10.1016/j.stem.2015.09.011

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