Cargando…

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

The generation of genetically-modified organisms has been revolutionized by the development of new genome editing technologies based on the use of gene-specific nucleases, such as meganucleases, ZFNs, TALENs and CRISPRs-Cas9 systems. The most rapid and cost-effective way to generate genetically-modi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ménoret, Séverine, De Cian, Anne, Tesson, Laurent, Remy, Séverine, Usal, Claire, Boulé, Jean-Baptiste, Boix, Charlotte, Fontanière, Sandra, Crénéguy, Alison, Nguyen, Tuan H., Brusselle, Lucas, Thinard, Reynald, Gauguier, Dominique, Concordet, Jean-Paul, Cherifi, Yacine, Fraichard, Alexandre, Giovannangeli, Carine, Anegon, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595769/
https://www.ncbi.nlm.nih.gov/pubmed/26442875
http://dx.doi.org/10.1038/srep14410