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Chemiluminometric Immunosensor for High-Sensitivity Cardiac Troponin I Employing a Polymerized Enzyme Conjugate as a Tracer

To detect high-sensitivity cardiac troponin I (hs-cTnI; <0.01 ng/mL) at points of care, we developed a rapid immunosensor by using horseradish peroxidase polymerized in 20 molecules on average (Poly-HRP) as a tracer conjugated with streptavidin (SA-Poly-HRP). As shown in the conventional system,...

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Detalles Bibliográficos
Autores principales: Lim, Guei-Sam, Seo, Sung-Min, Paek, Sung-Ho, Kim, Seung-Wan, Jeon, Jin-Woo, Kim, Dong-Hyung, Cho, Il-Hoon, Paek, Se-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595837/
https://www.ncbi.nlm.nih.gov/pubmed/26442606
http://dx.doi.org/10.1038/srep14848