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Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design

The aim was to determine the release-modifying effect of carboxymethyl xyloglucan for oral drug delivery. Sustained release matrix tablets of tramadol HCl were prepared by wet granulation method using carboxymethyl xyloglucan as matrix forming polymer. HPMC K100M was used in a small amount to contro...

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Detalles Bibliográficos
Autores principales:	Madgulkar, Ashwini R., Bhalekar, Mangesh R., Padalkar, Rahul R., Shaikh, Mohseen Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595968/ https://www.ncbi.nlm.nih.gov/pubmed/26555977 http://dx.doi.org/10.1155/2013/396468

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