Cargando…

Imatinib treatment reduces brain injury in a murine model of traumatic brain injury

Current therapies for Traumatic brain injury (TBI) focus on stabilizing individuals and on preventing further damage from the secondary consequences of TBI. A major complication of TBI is cerebral edema, which can be caused by the loss of blood brain barrier (BBB) integrity. Recent studies in severa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Enming J., Fredriksson, Linda, Kanzawa, Mia, Moore, Shannon, Folestad, Erika, Stevenson, Tamara K., Nilsson, Ingrid, Sashindranath, Maithili, Schielke, Gerald P., Warnock, Mark, Ragsdale, Margaret, Mann, Kris, Lawrence, Anna-Lisa E., Medcalf, Robert L., Eriksson, Ulf, Murphy, Geoffrey G., Lawrence, Daniel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596067/ https://www.ncbi.nlm.nih.gov/pubmed/26500491 http://dx.doi.org/10.3389/fncel.2015.00385

Ejemplares similares

Opposing effects of β-2 and β-1 adrenergic receptor signaling on neuroinflammation and dopaminergic neuron survival in α-synuclein-mediated neurotoxicity
por: Torrente, Daniel, et al.
Publicado: (2023)

Identification of a neurovascular signaling pathway regulating seizures in mice
por: Fredriksson, Linda, et al.
Publicado: (2015)

Endothelial Dysfunction in the Brain: Setting the Stage for Stroke and Other Cerebrovascular Complications of COVID-19
por: Sashindranath, Maithili, et al.
Publicado: (2021)

Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes
por: Crack, Peter J, et al.
Publicado: (2014)

Imatinib Enhances Functional Outcome after Spinal Cord Injury
por: Abrams, Mathew B., et al.
Publicado: (2012)

Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke
por: Su, Enming Joseph, et al.
Publicado: (2017)

Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury123
por: Karve, Ila P., et al.
Publicado: (2016)

Traumatic Brain Injury Leads to Accelerated Atherosclerosis in Apolipoprotein E Deficient Mice
por: Wang, Jintao, et al.
Publicado: (2018)

Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response
por: Z. Adzemovic, Milena, et al.
Publicado: (2013)

Correction: Imatinib Ameliorates Neuroinflammation in a Rat Model of Multiple Sclerosis by Enhancing Blood-Brain Barrier Integrity and by Modulating the Peripheral Immune Response
por: Z. Adzemovic, Milena, et al.
Publicado: (2013)

Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice
por: Wang, Jintao, et al.
Publicado: (2023)

Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers
por: Kjell, Jacob, et al.
Publicado: (2015)

Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCβ phosphorylation of occludin
por: Goncalves, Andreia, et al.
Publicado: (2022)

Niche Cells Crosstalk In Neuroinflammation After Traumatic Brain Injury
por: Jia, Yibin, et al.
Publicado: (2021)

Top-Cited Articles in Traumatic Brain Injury
por: Sharma, Bhanu, et al.
Publicado: (2014)

Repositioning imatinib for spinal cord injury
por: Kjell, Jacob, et al.
Publicado: (2015)

Characterization of Tissue Plasminogen Activator Expression and Trafficking in the Adult Murine Brain
por: Stevenson, Tamara K., et al.
Publicado: (2018)

Characterization of a novel model of global forebrain ischaemia–reperfusion injury in mice and comparison with focal ischaemic and haemorrhagic stroke
por: Lee, Natasha Ting, et al.
Publicado: (2020)

CD39 in the development and progression of pulmonary arterial hypertension
por: Willcox, Abbey, et al.
Publicado: (2022)

Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype
por: Gladh, Hanna, et al.
Publicado: (2016)

The potential role of protease systems in hemophilic arthropathy
por: Hauw, Wayne W. S., et al.
Publicado: (2022)

Responsiveness of the Traumatic Brain Injury Quality of Life Cognition Banks in Recent Brain Injury
por: Tyner, Callie E., et al.
Publicado: (2022)

Traumatic Brain Injuries: Comprehensive Management of Complex Clinical Scenarios
por: Ganau, Mario, et al.
Publicado: (2023)

Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib
por: Alexandru, Daniela, et al.
Publicado: (2009)

Traumatic Brain Injury: Current Treatment Strategies and Future Endeavors
por: Galgano, Michael, et al.
Publicado: (2017)

Cellular infiltration in traumatic brain injury
por: Alam, Aftab, et al.
Publicado: (2020)

Traumatic brain injury and immunological outcomes: the double-edged killer
por: Datta, Souvik, et al.
Publicado: (2023)

Learning following Brain Injury: Neural Plasticity Markers
por: Carey, Leeanne, et al.
Publicado: (2019)

Do corticosteroids play a role in the management of traumatic brain injury?
por: Hoshide, Reid, et al.
Publicado: (2016)

Children and youth with ‘unspecified injury to the head’: implications for traumatic brain injury research and surveillance
por: Chan, Vincy, et al.
Publicado: (2015)

Electrolyte disturbances and acute kidney injury induced by imatinib therapy
por: de Oliveira, Rodrigo Azevedo, et al.
Publicado: (2009)

Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier
por: Zeitelhofer, Manuel, et al.
Publicado: (2020)

TRANSCRANIAL AMELIORATION OF INFLAMMATION AND CELL DEATH FOLLOWING BRAIN INJURY
por: Roth, Theodore L., et al.
Publicado: (2013)

Biomarkers of Brain Injury: A Window on Mechanisms of Injury and Recovery in the Brain
por: Bagnato, Sergio
Publicado: (2022)

Trends in North American Newspaper Reporting of Brain Injury in Ice Hockey
por: Cusimano, Michael D., et al.
Publicado: (2013)

Stem Cell Therapy for Sequestration of Traumatic Brain Injury-Induced Inflammation
por: Borlongan, Mia C., et al.
Publicado: (2022)

Brain Immune Interactions—Novel Emerging Options to Treat Acute Ischemic Brain Injury
por: Muhammad, Sajjad, et al.
Publicado: (2021)

Theta-Band Oscillations as an Indicator of Mild Traumatic Brain Injury
por: Kaltiainen, Hanna, et al.
Publicado: (2018)

The Neurobiology of Brain Injury
por: Pekna, Marcela, et al.
Publicado: (2012)

Mild Brain Injury
por: Greenwald, Brian D., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jkli7u8kbqt1vghsrr2s7ql14f