Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants

A series of mitochondria-targeted antioxidants comprising a lipophilic triphenylphosphonium cation attached to the antioxidant chroman moiety of vitamin E by an alkyl linker have been prepared. The synthesis of a series of mitochondria-targeted vitamin E derivatives with a range of alkyl linkers gav...

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Detalles Bibliográficos
Autores principales: Jameson, Victoria J.A., Cochemé, Helena M., Logan, Angela, Hanton, Lyall R., Smith, Robin A.J., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596152/
https://www.ncbi.nlm.nih.gov/pubmed/26549895
http://dx.doi.org/10.1016/j.tet.2015.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596152/
https://www.ncbi.nlm.nih.gov/pubmed/26549895
http://dx.doi.org/10.1016/j.tet.2015.09.014

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