UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration

Neurodegenerative diseases are a leading cause of disability and early death. A common feature of these conditions is disruption of protein homeostasis. Ubiquitin-like modifier activating enzyme 1 (UBA1), the E1 ubiquitin-activating enzyme, sits at the apex of the ubiquitin cascade and represents an...

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Detalles Bibliográficos
Autores principales: Groen, Ewout J.N., Gillingwater, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596250/
https://www.ncbi.nlm.nih.gov/pubmed/26432019
http://dx.doi.org/10.1016/j.molmed.2015.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596250/
https://www.ncbi.nlm.nih.gov/pubmed/26432019
http://dx.doi.org/10.1016/j.molmed.2015.08.003

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